SCHEMBL17028627

SCHEMBL17028627

CCC(Cc1ccc(OCc2cc(F)ccc2Br)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 8/20 0.52
PPARD Q03181 6/20 0.52
MME P08473 2/20 0.49
ACE P12821 2/20 0.49
CPA1 P15085 2/20 0.49
ACE2 Q9BYF1 2/20 0.49
PPARG P37231 6/20 0.47
EPHX2 P34913 1/20 0.46
FFAR1 O14842 6/20 0.46
FFAR4 Q5NUL3 6/20 0.46
GPR34 Q9UPC5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12713224 0.81 PPARG (0.47) PPARAPPARDPPARGEPHX2
SCHEMBL17028719 0.80 FFAR4 (0.49) MMEACECPA1ACE2FFAR1
SCHEMBL17028704 0.79 FFAR4 (0.56) PPARAPPARDMMEACECPA1
SCHEMBL17028629 0.77 FFAR1 (0.56) FFAR1FFAR4
SCHEMBL5378074 0.75 CYP1A2 (0.57) PPARAPPARDCPA1PPARGEPHX2
SCHEMBL15265930 0.75 FFAR4 (0.53) FFAR1FFAR4
SCHEMBL28441594 0.75 PPARA (0.62) PPARAPPARDMMEACECPA1
SCHEMBL15265470 0.74 FFAR4 (0.53) FFAR1FFAR4
SCHEMBL15265030 0.73 FFAR4 (0.49) FFAR1FFAR4
SCHEMBL17028712 0.73 FFAR4 (0.59) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107901-B1 COMPOUNDS FOR USE AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2020-04-01 EP disclosed
US-10227360-B2 Compounds for use as GPR120 agonists Piramal Enterprises Limited (IN) 2019-03-12 US disclosed
EP-3107901-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-28 EP disclosed
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-01 US disclosed
WO-2015125085-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227360-B2 Compounds for use as GPR120 agonists GPR119, GPR55, GPR180 PPARA 190/4885PPARD 117/4885MME 3089/4885
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS GPR119, GPR55, GPR180 PPARA 190/4885PPARD 117/4885MME 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.