Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751332 | 0.81 | MAPT (0.31) | L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL17028979 | 0.81 | LTA4H (0.42) | HAO1MAOAMAOBLTA4HHTT | |
| SCHEMBL2751993 | 0.81 | MEN1 (0.55) | HAO1MEN1KMT2A | |
| SCHEMBL2749592 | 0.76 | CYP1A2 (0.38) | HTTSCN9ACYP2C9CYP1A2CYP2C19 | |
| SCHEMBL2752786 | 0.76 | TTR (0.45) | LMNAPTGS1PTGS2MAPTHPGD | |
| SCHEMBL2752064 | 0.74 | HAO1 (0.44) | HAO1HTTL3MBTL1NPSR1SMN1; SMN2 | |
| SCHEMBL971751 | 0.74 | CHRNB2 (0.33) | GAA | |
| SCHEMBL973593 | 0.73 | CA1 (0.49) | L3MBTL1NPSR1SMN1; SMN2LMNATSHR | |
| SCHEMBL2750533 | 0.71 | CA2 (0.47) | HTTL3MBTL1CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL2751328 | 0.70 | ALDH1A1 (0.37) | NPSR1CYP2C9SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124606-A1 | N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-27 | — | — | WO | disclosed |