Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22297856 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL17029298 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL8038145 | 0.82 | GRIN1 (0.48) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL16656265 | 0.82 | GRIN1 (0.48) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL7556163 | 0.81 | SIGMAR1 (0.65) | ALDH1A1SIGMAR1DRD4SLC6A9ATM | |
| SCHEMBL8510915 | 0.81 | ITGB3 (0.56) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL9610969 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL2717435 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL16641754 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL21044023 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115172-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |