Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039773 | 0.84 | CNR2 (0.45) | HPGDALDH1A1RORCALOX15HSP90AA1 | |
| SCHEMBL4349254 | 0.81 | NPY5R (0.46) | NPY5RHPGDNAMPTALDH1A1RORC | |
| Hydrochloric Acid SCHEMBL4349336 | 0.80 | NPY5R (0.45) | NPY5RHPGDNAMPTALDH1A1RORC | |
| SCHEMBL4491486 | 0.76 | HPGD (0.53) | NPY5RHPGDALDH1A1HSD17B10HSP90AA1 | |
| SCHEMBL10286193 | 0.76 | KMT2A (0.46) | NPY5RHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL9250331 | 0.75 | TAAR1 (0.45) | NPY5RHPGDALDH1A1RORCHSD17B10 | |
| SCHEMBL4349128 | 0.75 | NPY5R (0.43) | NPY5RHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL29958161 | 0.74 | LPL (0.48) | NPY5RHSP90AA1KDM4ECA1CA2 | |
| SCHEMBL3174757 | 0.74 | HSP90AA1 (0.57) | NPY5RHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL6180312 | 0.73 | RORC (0.48) | NPY5RHPGDRORCHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137164-B1 | INHIBITORS OF PROTEIN KINASES | ASTRAZENECA AB (SE) | 2015-08-26 | — | — | EP | disclosed |