Diphenylsulfane

Diphenylsulfane

SCHEMBL1702976

[O-][S+]1c2ccccc2Cc2ccccc21.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.34
MAOB P27338 3/20 0.34
HPGD P15428 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 1/20 0.31
MGLL Q99685 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MMP8 P22894 3/20 0.31
MMP3 P08254 2/20 0.31
HTR2C P28335 2/20 0.30
MMP13 P45452 1/20 0.30
HTR6 P50406 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128377 0.90 MAOA (0.36) MAOAMAOBHPGDALDH1A1SMN1; SMN2
SCHEMBL9160477 0.85 MAOA (0.39) MAOAMAOBHPGDALDH1A1SMN1; SMN2
SCHEMBL10476775 0.85 MAOA (0.39) MAOAMAOBHPGDALDH1A1SMN1; SMN2
SCHEMBL36333 0.85 MAOA (0.39) MAOAMAOBHPGDALDH1A1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL1871983 0.83 MAOA (0.37) MAOAMAOBHPGDALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL585839 0.83 MAOA (0.37) MAOAMAOBHPGDALDH1A1SMN1; SMN2
SCHEMBL1128512 0.82
Ethylene SCHEMBL9721427 0.81 MAOA (0.36) MAOAMAOBHSD17B10HTR2C
Bicarbonate SCHEMBL8096283 0.80 SRD5A2 (0.38) MAOAMAOBALDH1A1MAPTHSD17B10
Trimethylammonium SCHEMBL10477929 0.78 HTR2A (0.37) MAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101952269-B Sulphonium salt initiators BASF SE 2014-06-25 CN disclosed
US-8652752-B2 Sulphonium salt initiators BASF SE (DE) 2014-02-18 US disclosed
EP-2197869-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2013-04-24 EP disclosed
CN-101522613-B Sulphonium salt photoinitiators CIBA HOLDING INC 2013-03-06 CN disclosed
EP-2197839-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2013-01-02 EP disclosed
EP-2125713-B1 SULPHONIUM SALT PHOTOINITIATORS BASF SE (DE) 2012-04-18 EP disclosed
US-8012672-B2 Sulphonium salt photoinitiators BASF SE (DE) 2011-09-06 US disclosed
CN-101952269-A Sulphonium salt initiators BASF SE 2011-01-19 CN disclosed
US-20100297541-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-11-25 US disclosed
US-20100297540-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-11-25 US disclosed
EP-2197839-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 EP disclosed
EP-2197869-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 EP disclosed
US-20100087563-A1 SULPHONIUM SALT PHOTOINITIATORS BASF SE (DE) 2010-04-08 US disclosed
EP-2125713-A1 SULPHONIUM SALT PHOTOINITIATORS Ciba SC Holding AG (CH) 2009-12-02 EP disclosed
CN-101522613-A Sulphonium salt photoinitiators CIBA SC HOLDING AG (CH) 2009-09-02 CN disclosed
WO-2009047152-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 WO disclosed
WO-2009047105-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 WO disclosed
WO-2008040648-A1 SULPHONIUM SALT PHOTOINITIATORS CIBA HOLDING INC. (CH) 2008-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087563-A1 SULPHONIUM SALT PHOTOINITIATORS SULT1A1, NCOR1, ARSA MAOA 1253/4885MAOB 2187/4885HPGD 2449/4885
US-20100297540-A1 SULPHONIUM SALT INITIATORS SULT1A1, SULT2A1, NCOA1 MAOA 2820/4885MAOB 4087/4885HPGD 3606/4885
US-20100297541-A1 SULPHONIUM SALT INITIATORS NCOR1, NCOR2, SMARCC2 MAOA 4545/4885MAOB 3581/4885HPGD 4440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.