Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703010 | 1.00 | MAOB (0.50) | MAOBGSK3BCYP1A2KDM4ENOS2 | |
| SCHEMBL16865336 | 0.88 | KDM4E (0.53) | MAOBGSK3BCYP1A2KDM4ENOS2 | |
| SCHEMBL11087873 | 0.88 | RAB9A (0.54) | MAOBGSK3BKDM4EALDH1A1GAA | |
| SCHEMBL11087866 | 0.88 | RAB9A (0.54) | MAOBGSK3BKDM4EALDH1A1GAA | |
| SCHEMBL9297329 | 0.88 | KDM4E (0.53) | MAOBGSK3BCYP1A2KDM4ENOS2 | |
| SCHEMBL3763701 | 0.86 | GSK3B (0.58) | MAOBGSK3BCYP1A2NOS2NOS3 | |
| SCHEMBL3763704 | 0.86 | GSK3B (0.58) | MAOBGSK3BCYP1A2NOS2NOS3 | |
| SCHEMBL7423208 | 0.85 | HAO1 (0.63) | MAOBGSK3BKDM4ETDP1ALDH1A1 | |
| SCHEMBL7423204 | 0.85 | HAO1 (0.63) | MAOBGSK3BKDM4ETDP1ALDH1A1 | |
| SCHEMBL11087303 | 0.84 | GSK3B (0.74) | MAOBGSK3BCYP1A2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440526-B1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-11-12 | — | — | EP | disclosed |
| EP-2440526-B1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8598086-B2 | 3-halo-(arly)-4-iminotetrahydropicolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2440530-B1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2013-07-24 | — | — | EP | disclosed |
| EP-2440530-B1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2013-07-24 | — | — | EP | disclosed |
| US-8252938-B2 | Process for the preparation of 6-(aryl)-4-aminopicolinates | DOW AGROSCIENCES, LLC. (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252938-B2 | Process for the preparation of 6-(aryl)-4-aminopicolinates | DOW AGROSCIENCES, LLC. (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252938-B2 | Process for the preparation of 6-(aryl)-4-aminopicolinates | DOW AGROSCIENCES, LLC. (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2440526-A1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144380-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010144379-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | HTR6, CYP46A1, NISCH | MAOB 1379/4885GSK3B 3794/4885CYP1A2 483/4885 |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | HDHD5, ATL3, HCAR3 | MAOB 2953/4885GSK3B 1765/4885CYP1A2 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.