Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11874480 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11864583 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11874772 | 0.79 | LMNA (0.62) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11867992 | 0.78 | NOTUM (0.56) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL17033346 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11872653 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11870188 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11865738 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11867054 | 0.73 | GAA (0.51) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11872403 | 0.72 | KMT2A (0.50) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | ALDH1A1 3080/4885MEN1 4188/4885KMT2A 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.