Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706518 | 0.86 | TDP1 (0.40) | MEN1KMT2ATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL15179706 | 0.84 | CA1 (0.36) | SMN1; SMN2ACACBACACAPPARGPPARD | |
| SCHEMBL17039675 | 0.84 | MEN1 (0.42) | MEN1KMT2ATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL29324089 | 0.82 | LTA4H (0.47) | MEN1KMT2ASMN1; SMN2MAPK1TSHR | |
| SCHEMBL15179674 | 0.81 | ELANE (0.54) | SMN1; SMN2ALDH1A1TSHRESR1ELANE | |
| SCHEMBL116844 | 0.81 | THRB (0.51) | MEN1KMT2ATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL12716906 | 0.81 | CHRNB2 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL14015406 | 0.79 | PTPRC (0.49) | MAPK1TP53TSHRPPARAGAA | |
| SCHEMBL12793181 | 0.79 | HDAC1 (0.50) | SMN1; SMN2PPARA | |
| SCHEMBL11991306 | 0.79 | POLB (0.41) | MEN1KMT2ATDP1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150241779-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150241779-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-08-27 | — | — | US | disclosed |