Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499446 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2AMAPTEGFRLMNA | |
| SCHEMBL23480399 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KMT2AGFERHPGDMAOB | |
| SCHEMBL12123627 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KMT2AGFERHPGDMAOB | |
| SCHEMBL12123636 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KMT2AGFERHPGDMAOB | |
| SCHEMBL11218157 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KMT2AGFERHPGDMAOB | |
| Hydrochloric Acid SCHEMBL7929065 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AGFERHPGDMAOB | |
| SCHEMBL10107784 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2AGFERHPGDMAPT | |
| SCHEMBL5356971 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2AGFERHPGDMAPT | |
| SCHEMBL13181438 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KMT2AGFERHPGDMAOB | |
| SCHEMBL13069210 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2AGFERHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | ALDH1A1 3080/4885KMT2A 4493/4885GFER 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.