Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | GFER | P55789 | 1/20 | 0.97 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10107784 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AGFERMAPTEGFR | |
| Hydrochloric Acid SCHEMBL10675086 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KMT2AGFERMAPTEGFR | |
| Hydrochloric Acid SCHEMBL29354698 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KMT2AGFERMAPTEGFR | |
| SCHEMBL10507206 | 0.98 | ALDH1A1 (0.96) | ALDH1A1KMT2AGFERMAPTEGFR | |
| Hydrochloric Acid SCHEMBL10670221 | 0.96 | ALDH1A1 (0.97) | ALDH1A1KMT2AGFERMAPTEGFR | |
| SCHEMBL2725965 | 0.95 | KMT2A (0.90) | ALDH1A1KMT2AGFERMAPTEGFR | |
| SCHEMBL16026463 | 0.91 | KMT2A (0.83) | ALDH1A1KMT2AGFERMAPTSIGMAR1 | |
| SCHEMBL10603564 | 0.90 | ALDH1A1 (0.81) | ALDH1A1KMT2AGFERMAPTEGFR | |
| SCHEMBL7645836 | 0.90 | ALDH1A1 (0.81) | ALDH1A1KMT2AGFERMAPTEGFR | |
| Hydrochloric Acid SCHEMBL7934846 | 0.89 | KMT2A (0.83) | ALDH1A1KMT2AGFERMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114767624-A | Pharmaceutical composition containing 4-butoxy-beta-piperidyl propiophenone compound and preparation method and application thereof | 南京唯创远医药科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-102030723-B | Preparation method of trihexyphenidyl hydrochloride | CHANGZHOU KANGPU PHARMACEUTICAL CO LTD | 2012-07-04 | — | — | CN | claimed |
| CN-102030723-A | Preparation method of trihexyphenidyl hydrochloride | CHANGZHOU KANGPU PHARMACEUTICAL CO LTD | 2011-04-27 | — | — | CN | claimed |
| CN-101311171-A | Compound with dual restraining activities to acetyl cholinesterase and butyryl cholinesterase and use thereof | INST MATERIA MEDICA CAMS (CN) | 2008-11-26 | — | — | CN | claimed |
| US-7307091-B2 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2007-12-11 | — | — | US | claimed |
| EP-1383752-B1 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEV AG (CH) | 2005-06-22 | — | — | EP | claimed |
| US-20040186136-A1 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2004-09-23 | — | — | US | claimed |
| EP-1383752-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | Turicum Drug Development AG (CH) | 2004-01-28 | — | — | EP | claimed |
| WO-2002088100-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEVELOPMENT AG (CH) | 2002-11-07 | — | — | WO | claimed |
| JP-6048997-A | — | — | None | — | — | JP | disclosed |
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114767624-A | Pharmaceutical composition containing 4-butoxy-beta-piperidyl propiophenone compound and preparation method and application thereof | 南京唯创远医药科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-113214141-B | 5HT2A receptor antagonists, their preparation and use | 瀚远医药有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-5798351-A | USEFUL FOR INHIBITING BONE LOSS, LOWERING SEUM CHOLESTEROL LEVELS AND TREATING HORMONE DEPENDENT MAMMALIAN BREAST AND UTERINE CANCER | ELI LILLY AND COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| JP-H0648997-A | ANTIVIRAL AGENT | SANWA KAGAKU KENKYUSHO CO LTD | 1994-02-22 | — | — | JP | disclosed |
| EP-0558321-A1 | Antivirally active N-cycloalkyl alkanol compounds | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4065565-A | Acylhydrazones and anti-psychotic compositions thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-12-27 | — | — | US | disclosed |
| US-3962256-A | ANALGESICS, HYPOTENSIVES, ANTIINFLAMMATORY AGENTS | DELALANDE S.A. (FR) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186136-A1 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | MUSK, CPT1B, PYGM | ALDH1A1 1601/4885KMT2A 2621/4885GFER 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.