Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034359 | 0.98 | TGM2 (0.46) | TGM2HTTTHRBALDH1A1CYP3A4 | |
| SCHEMBL17034300 | 0.96 | TGM2 (0.45) | TGM2HTTTHRBLMNASMN1; SMN2 | |
| SCHEMBL17034350 | 0.94 | TGM2 (0.43) | TGM2HTTTHRBLMNASMN1; SMN2 | |
| SCHEMBL17034292 | 0.92 | LMNA (0.42) | TGM2HTTTHRBLMNASMN1; SMN2 | |
| SCHEMBL17034357 | 0.90 | THRB (0.40) | TGM2HTTTHRBLMNASMN1; SMN2 | |
| SCHEMBL17034219 | 0.86 | TGM2 (0.51) | TGM2HTTTHRB | |
| SCHEMBL17034293 | 0.86 | TGM2 (0.41) | TGM2HTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL17034335 | 0.84 | HTT (0.40) | TGM2HTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL17034132 | 0.83 | TGM2 (0.47) | TGM2THRB | |
| SCHEMBL17034209 | 0.82 | THRB (0.40) | TGM2THRBALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |