Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034300 | 0.98 | TGM2 (0.45) | TGM2THRBL3MBTL1LMNAALDH1A1 | |
| SCHEMBL17034359 | 0.96 | TGM2 (0.46) | TGM2THRBALDH1A1HTT | |
| SCHEMBL17034272 | 0.94 | TGM2 (0.48) | TGM2THRBL3MBTL1LMNAALDH1A1 | |
| SCHEMBL17034357 | 0.94 | THRB (0.40) | TGM2THRBL3MBTL1LMNAMAPT | |
| SCHEMBL17034292 | 0.92 | LMNA (0.42) | TGM2THRBL3MBTL1LMNAMAPT | |
| SCHEMBL17036959 | 0.85 | THRB (0.43) | THRBL3MBTL1SMN1; SMN2 | |
| SCHEMBL17034347 | 0.85 | THRB (0.45) | TGM2THRBL3MBTL1MAPT | |
| SCHEMBL17034270 | 0.84 | TGM2 (0.47) | TGM2THRBL3MBTL1MAPTHTT | |
| SCHEMBL17034351 | 0.83 | L3MBTL1 (0.39) | L3MBTL1LMNAALDH1A1MAPTHTT | |
| SCHEMBL17034278 | 0.83 | L3MBTL1 (0.41) | TGM2L3MBTL1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |