SCHEMBL17034871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17034874	0.96	CYP19A1 (0.48)	CYP11B1CYP19A1CYP17A1CYP11B2DHODH
	SCHEMBL18201009	0.92	CYP1A2 (0.50)	HPGDCYP1A2CYP3A4ALDH1A1KMT2A
	SCHEMBL18201241	0.91	CYP1A2 (0.51)	HPGDCYP1A2CYP3A4ALDH1A1KMT2A
	SCHEMBL18200999	0.90	CYP19A1 (0.58)	CYP11B1CYP19A1CYP17A1CYP11B2DHODH
	SCHEMBL18201052	0.90	DHODH (0.47)	CYP11B1CYP19A1CYP17A1CYP11B2DHODH
	SCHEMBL17034881	0.90	CYP11B1 (0.49)	CYP11B1CYP19A1CYP17A1CYP11B2DHODH
	SCHEMBL18201000	0.89	ALDH1A1 (0.47)	HPGDCYP1A2CYP3A4ALDH1A1KMT2A
	SCHEMBL18201054	0.89	DHODH (0.46)	CYP11B1CYP19A1CYP17A1CYP11B2DHODH
	SCHEMBL18200601	0.89	NUDT1 (0.47)	DHODHHPGDALDH1A1KMT2AMEN1
	SCHEMBL18200600	0.89	NUDT1 (0.47)	DHODHHPGDALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.