Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626902 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL11018105 | 0.86 | KMT2A (0.49) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL17036996 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL27709852 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL2108251 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL12587683 | 0.80 | ALDH1A1 (0.57) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL5494961 | 0.79 | TDP1 (0.55) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL15140443 | 0.79 | MEN1 (0.51) | ALDH1A1TSHRKMT2AMEN1TDP1 | |
| SCHEMBL13328780 | 0.79 | KDM4E (0.56) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL11959217 | 0.78 | LMNA (0.58) | TSHRKMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | TYR, MITF, MC1R | ALDH1A1 2374/4885TSHR 873/4885KMT2A 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.