SCHEMBL17037262

SCHEMBL17037262

N#Cc1ccc(-c2nc3ccccc3c3c2ccc2ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
ADORA2A P29274 1/20 0.43
ABCG2 Q9UNQ0 3/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
ABCB1 P08183 1/20 0.41
PDPK1 O15530 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PDE10A Q9Y233 1/20 0.40
HSD11B1 P28845 1/20 0.40
TDO2 P48775 1/20 0.39
ALOX5 P09917 1/20 0.39
SLC22A12 Q96S37 1/20 0.39
KDM1A O60341 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17037161 0.89 MEN1 (0.41) MEN1KMT2AATMADORA2AABCG2
SCHEMBL17037347 0.88 ABCG2 (0.44) MEN1KMT2AATMADORA2AABCG2
SCHEMBL17037284 0.86 ABCG2 (0.45) MEN1KMT2AATMADORA2AABCG2
SCHEMBL18200601 0.85 NUDT1 (0.47) MEN1KMT2AATMADORA2AALDH1A1
SCHEMBL18200600 0.85 NUDT1 (0.47) MEN1KMT2AATMADORA2AALDH1A1
SCHEMBL17034863 0.85 NUDT1 (0.50) MEN1KMT2AATMADORA2AALDH1A1
SCHEMBL24422791 0.83 MEN1 (0.43) MEN1KMT2AATMADORA2AABCG2
SCHEMBL17037346 0.83 CA1 (0.36) MEN1KMT2AATMADORA2AABCG2
SCHEMBL24422298 0.82 ALDH1A1 (0.45) MEN1KMT2AATMADORA2AABCG2
SCHEMBL17037211 0.82 PIM1 (0.37) MEN1KMT2AATMADORA2AABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9871208-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-16 US disclosed
US-20150243908-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-27 US disclosed
US-20150243895-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243908-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MEN1 476/4885KMT2A 2092/4885ATM 1334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.