Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 4/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21086948 | 1.00 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL21150195 | 1.00 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL17026587 | 0.90 | TK1 (0.39) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL17026588 | 0.90 | TK1 (0.39) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL17026544 | 0.90 | TK1 (0.40) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16964214 | 0.90 | TK1 (0.40) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16964213 | 0.90 | TK1 (0.40) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL17026546 | 0.90 | TK1 (0.40) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL17037310 | 0.83 | TK1 (0.45) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL21151113 | 0.78 | HIF1A (0.45) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175633-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2019-06-13 | — | — | US | disclosed |
| US-20150240295-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
| US-20150240295-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150240295-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | NCL, NOP2, POLRMT | LMNA 541/4885SMN1; SMN2 3901/4885ALOX12 1116/4885 |
| US-20190175633-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | NCL, NOP2, HNRNPD | LMNA 255/4885SMN1; SMN2 3552/4885ALOX12 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.