Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12880105 | 1.00 | TDP1 (0.40) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3127227 | 0.85 | CA2 (0.41) | CA1CA2FDPSFAAH | |
| SCHEMBL8258858 | 0.83 | CA1 (0.48) | CA1CA2FDPSFAAH | |
| SCHEMBL12641501 | 0.82 | CHRM1 (0.39) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL18024824 | 0.81 | FAAH (0.47) | CA1CA2FDPSFAAH | |
| SCHEMBL4575363 | 0.81 | CHRM1 (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3651519 | 0.79 | CHRM1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL20490010 | 0.79 | CHRM1 (0.40) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28854124 | 0.79 | ALDH1A1 (0.33) | TDP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13251398 | 0.79 | CA1 (0.39) | TDP1CA1CA2ALDH1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10685844-B2 | Hardmask composition, method of forming pattern by using the hardmask composition, and hardmask formed using the hardmask composition | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-06-16 | — | — | US | claimed |
| US-20190035635-A1 | HARDMASK COMPOSITION, METHOD OF FORMING PATTERN BY USING THE HARDMASK COMPOSITION, AND HARDMASK FORMED USING THE HARDMASK COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-01-31 | — | — | US | claimed |
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20150239866-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK CANADA INC. (CA) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190035635-A1 | HARDMASK COMPOSITION, METHOD OF FORMING PATTERN BY USING THE HARDMASK COMPOSITION, AND HARDMASK FORMED USING THE HARDMASK COMPOSITION | DEK, HNRNPK, DGKA | TDP1 3397/4885CHRM1 2216/4885AKR1A1 3809/4885 |
| US-20150239866-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | SYK, BTK, TYRO3 | TDP1 678/4885CHRM1 1688/4885AKR1A1 2541/4885 |
| US-10685844-B2 | Hardmask composition, method of forming pattern by using the hardmask composition, and hardmask formed using the hardmask composition | DEK, HNRNPK, DGKA | TDP1 3397/4885CHRM1 2216/4885AKR1A1 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.