Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.55 |
| ▸ | WNT3A | P56704 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL992300 | 0.98 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4132169 | 0.94 | ALDH1A1 (0.61) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4120551 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL16419608 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL14152319 | 0.83 | CTNNB1 (0.53) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL2216212 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL15974627 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL352556 | 0.81 | ALDH1A1 (0.72) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL15974201 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3177576 | 0.79 | LMNA (0.77) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365927-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2025-07-22 | — | — | US | claimed |
| CN-119842647-A | Dehydrogenase mutant for synthesizing duloxetine intermediate and application thereof | 苏州诺恩斯生物科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| US-20230104779-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2023-04-06 | — | — | US | claimed |
| US-11512332-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2022-11-29 | — | — | US | claimed |
| US-20200340025-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-10-29 | — | — | US | claimed |
| US-10752926-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2020-08-25 | — | — | US | claimed |
| US-20180251802-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-09-06 | — | — | US | claimed |
| US-10006069-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2018-06-26 | — | — | US | claimed |
| US-20170226546-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-08-10 | — | — | US | claimed |
| US-9657320-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2017-05-23 | — | — | US | claimed |
| US-7579484-B2 | Preparation of 3-methylamino-1-phenyl-1-propanone or 3-methylamino-1-(2-thienyl)-1-propanone; chemical intermediates to central nervous system drugs such as fluoxetine, tomoxetine | MERCK PATENT GMBH (DE) | 2009-08-25 | — | — | US | claimed |
| EP-1587802-B1 | PRODUCTION AND USE OF 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANONE | BASF AG (DE) | 2007-11-14 | — | — | EP | claimed |
| US-7259264-B2 | 3-methylamino-1-(2-thienyl)-1-propanone, production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-21 | — | — | US | claimed |
| US-20060128791-A1 | 3-Methylamino-1-(2-thienyl)-1-propanone, production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-15 | — | — | US | claimed |
| US-20060122405-A1 | Method for the production of monoalkylamino ketones | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | US | claimed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | claimed |
| EP-1587802-A1 | 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANONE, PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2005-10-26 | — | — | EP | claimed |
| EP-1532101-A1 | METHOD FOR THE PRODUCTION OF MONOALKYLAMINO KETONES | MERCK PATENT GmbH (DE) | 2005-05-25 | — | — | EP | claimed |
| WO-2004065376-A1 | 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANONE, PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | claimed |
| WO-2004020391-A1 | METHOD FOR THE PRODUCTION OF MONOALKYLAMINO KETONES | MERCK PATENT GMBH (DE) | 2004-03-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122405-A1 | Method for the production of monoalkylamino ketones | BCKDK, AKR7A2, AKR1C3 | ALDH1A1 66/4885LMNA 2694/4885MEN1 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.