Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.53 |
| ▸ | WNT3A | P56704 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135291 | 0.94 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL170394 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL691373 | 0.83 | LMNA (0.59) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL11663088 | 0.82 | HDAC1 (0.59) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL16404278 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL994292 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL691269 | 0.81 | LMNA (0.57) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL13518261 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL992300 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL13517942 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370323-B2 | Method for preparing chiral gamma-secondary amino alcohol | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2019-08-06 | — | — | US | disclosed |
| US-20170275240-A1 | METHOD FOR PREPARING CHIRAL gamma-SECONDARY AMINO ALCOHOL | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2017-09-28 | — | — | US | disclosed |
| US-20170275240-A1 | METHOD FOR PREPARING CHIRAL gamma-SECONDARY AMINO ALCOHOL | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2017-09-28 | — | — | US | disclosed |
| US-9228213-B2 | Polynucleotides encoding engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-9228213-B2 | Polynucleotides encoding engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20150031094-A1 | POLYNUCLEOTIDES ENCODING ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-01-29 | — | — | US | disclosed |
| US-20150031094-A1 | POLYNUCLEOTIDES ENCODING ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275240-A1 | METHOD FOR PREPARING CHIRAL gamma-SECONDARY AMINO ALCOHOL | AADAT, BCKDK, ADH5 | ALDH1A1 572/4885LMNA 3331/4885MEN1 3703/4885 |
| US-10370323-B2 | Method for preparing chiral gamma-secondary amino alcohol | AADAT, BCKDK, ADH5 | ALDH1A1 572/4885LMNA 3331/4885MEN1 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.