Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31517184 | 0.90 | ALDH1A1 (0.55) | ALDH1A1ALOX15FOLH1CYP2C9CYP2C8 | |
| SCHEMBL31517180 | 0.90 | ALDH1A1 (0.55) | ALDH1A1ALOX15FOLH1CYP2C9CYP2C8 | |
| Pyromellitic Acid SCHEMBL28311393 | 0.89 | ALDH1A1 (0.60) | ALDH1A1ALOX15FOLH1CYP2C9CYP2C8 | |
| SCHEMBL18364471 | 0.89 | FOLH1 (0.49) | ALDH1A1ALOX15FOLH1CYP2C9CYP2C8 | |
| SCHEMBL36145 | 0.86 | ALDH1A1 (0.72) | ALDH1A1ALOX15FOLH1CYP2C9ALOX12 | |
| SCHEMBL30028907 | 0.86 | ALDH1A1 (0.72) | ALDH1A1ALOX15FOLH1CYP2C9ALOX12 | |
| SCHEMBL31517115 | 0.85 | ACMSD (0.59) | ALDH1A1ALOX15FOLH1CYP2C9CYP2C8 | |
| SCHEMBL28039539 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ALOX15FOLH1CYP2C9CYP2C8 | |
| SCHEMBL30888405 | 0.84 | ALDH1A1 (0.62) | ALDH1A1ALOX15FOLH1CYP2C9ALOX12 | |
| SCHEMBL2944662 | 0.84 | ALDH1A1 (0.62) | ALDH1A1ALOX15FOLH1CYP2C9ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886130-A | Use of 2-thia-dibenzo [ e, h ] azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders | PLIVA ISTRAZIVACKI INST D O O (HR) | 2006-12-27 | — | — | CN | claimed |
| EP-4304766-A1 | MEMBRANE DEVICE | Evove Ltd (GB) | 2024-01-17 | — | — | EP | disclosed |
| EP-4304765-A1 | SPACER FOR A SPIRAL WOUND MEMBRANE | Evove Ltd (GB) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189793-A1 | MEMBRANE DEVICE | EVOVE LTD (GB) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022189785-A1 | SPACER FOR A SPIRAL WOUND MEMBRANE | EVOVE LTD (GB) | 2022-09-15 | — | — | WO | disclosed |
| CN-108424745-B | Active energy ray-polymerizable resin composition, adhesive, coating agent, laminate, and use of laminate | 东洋油墨SC控股株式会社 | 2021-06-15 | — | — | CN | disclosed |
| CN-107619409-B | Join Azulene diimide derivative, preparation method and application | 中国科学院上海有机化学研究所 | 2019-10-22 | — | — | CN | disclosed |
| US-10287304-B2 | Acid, solvent, and thermal resistant metal-organic frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-14 | — | — | US | disclosed |
| CN-107619409-A | Join Azulene diimide derivative, its preparation method and application | 中国科学院上海有机化学研究所 | 2018-01-23 | — | — | CN | disclosed |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
| WO-2015127033-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-27 | — | — | WO | disclosed |
| CN-1886130-A | Use of 2-thia-dibenzo [ e, h ] azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders | PLIVA ISTRAZIVACKI INST D O O (HR) | 2006-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287304-B2 | Acid, solvent, and thermal resistant metal-organic frameworks | HAO2, ASF1A, FTO | ALDH1A1 639/4885ALOX15 634/4885FOLH1 1623/4885 |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | HAO2, ASF1A, FTO | ALDH1A1 639/4885ALOX15 634/4885FOLH1 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.