Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876145 | 0.84 | CTSK (0.40) | EPHX2CTSKTP53PRKCAPRKCD | |
| SCHEMBL18509372 | 0.81 | TP53 (0.46) | EPHX2CTSKTP53POLBCNR1 | |
| SCHEMBL14175871 | 0.77 | TP53 (0.36) | TP53POLBMEN1MAPTKMT2A | |
| SCHEMBL27626107 | 0.77 | EPHX2 (0.39) | EPHX2CTSKCNR1DAGLAMAPT | |
| SCHEMBL5364963 | 0.77 | EPHX2 (0.39) | EPHX2CTSKCNR1DAGLAMAPT | |
| SCHEMBL5371935 | 0.76 | PRKCA (0.41) | EPHX2CTSKPRKCAPRKCDMAPT | |
| SCHEMBL30272012 | 0.75 | EPHX2 (0.47) | EPHX2CTSKCNR1DAGLAPRKCA | |
| SCHEMBL27300462 | 0.75 | SMN1; SMN2 (0.43) | EPHX2CTSKMEN1KMT2A | |
| SCHEMBL12588856 | 0.74 | TSHR (0.34) | TP53POLBMEN1MAPTKMT2A | |
| SCHEMBL5371355 | 0.73 | EPHX2 (0.37) | EPHX2CTSKTP53CNR1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150240157-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-08-27 | — | — | US | disclosed |