SCHEMBL5371935

SCHEMBL5371935

CCCC(CC)OC(=O)C1CCC(C(=O)OC(CC)CCC)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.41
PRKCD Q05655 2/20 0.41
EPHX2 P34913 2/20 0.41
CTSK P43235 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
ADRA1A P35348 2/20 0.32
CHRM2 P08172 1/20 0.32
CHRNA4 P43681 1/20 0.32
HTR3A P46098 1/20 0.32
KCNH2 Q12809 1/20 0.32
ACACB O00763 1/20 0.32
AKR1A1 P14550 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30272012 0.87 EPHX2 (0.47) PRKCAPRKCDEPHX2CTSKMAPT
SCHEMBL5375453 0.86 EPHX2 (0.52) PRKCAPRKCDEPHX2SMN1; SMN2LMNA
SCHEMBL27300462 0.83 SMN1; SMN2 (0.43) EPHX2CTSKSMN1; SMN2LMNACHRM1
SCHEMBL11229159 0.81 PRKCA (0.40) PRKCAPRKCDEPHX2CTSKSMN1; SMN2
SCHEMBL9876145 0.80 CTSK (0.40) PRKCAPRKCDEPHX2CTSKLMNA
SCHEMBL28264542 0.78 EPHX2 (0.35) PRKCAPRKCDEPHX2CTSKMAPT
SCHEMBL5371895 0.78 FAAH (0.34) CTSKSMN1; SMN2CHRM1CHRM3ADRA1A
SCHEMBL5370039 0.78 ACACB (0.36) EPHX2CTSKLMNAACACBMAPT
SCHEMBL10321962 0.78 ACACB (0.36) EPHX2CTSKLMNAACACBMAPT
SCHEMBL2986183 0.78 ACACB (0.36) EPHX2CTSKLMNAACACBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed