Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094974 | 0.84 | AGTR2 (0.73) | AGTR2AGTR1 | |
| SCHEMBL614372 | 0.83 | AGTR1 (0.77) | AGTR2AGTR1 | |
| SCHEMBL6555241 | 0.78 | AGTR1 (0.69) | AGTR2AGTR1 | |
| SCHEMBL8081205 | 0.78 | AGTR2 (0.64) | AGTR2AGTR1 | |
| SCHEMBL8089291 | 0.76 | AGTR1 (0.73) | AGTR2AGTR1 | |
| SCHEMBL9265644 | 0.76 | AGTR1 (0.69) | AGTR2AGTR1 | |
| SCHEMBL9571451 | 0.76 | AGTR1 (0.65) | AGTR2AGTR1 | |
| SCHEMBL8089288 | 0.76 | AGTR1 (0.60) | AGTR2AGTR1 | |
| SCHEMBL8091186 | 0.76 | AGTR1 (0.70) | AGTR2AGTR1 | |
| SCHEMBL7942058 | 0.76 | AGTR1 (0.78) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2296685-B1 | AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS | SYNERGY PHARMACEUTICALS INC (US) | 2015-09-02 | — | — | EP | disclosed |