Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089303 | 0.86 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8094974 | 0.85 | AGTR2 (0.73) | AGTR1AGTR2 | |
| SCHEMBL8089404 | 0.84 | AGTR2 (0.74) | AGTR1AGTR2 | |
| SCHEMBL8083218 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL8092921 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8081205 | 0.79 | AGTR2 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9031922 | 0.77 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8092909 | 0.77 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL1986629 | 0.77 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL269 | 0.77 | AGTR1 (0.85) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037349-A | HAVING ANTAGONISTIC PROPERTIES TOWARDS ANGIOTENSIN II CAN BE USED FOR THE TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5798364-A | ANGIOTENSIN II ANTAGONIST, USEFUL FOR TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-08-25 | — | — | US | disclosed |
| EP-0505893-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1992-09-30 | — | — | EP | disclosed |