SCHEMBL17044644

SCHEMBL17044644

O=S(=O)(O)c1ccc(CCBr)cc1.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
TSHR P16473 3/20 0.45
ALDH1A1 P00352 1/20 0.45
NT5E P21589 1/20 0.45
TDP1 Q9NUW8 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CA2 P00918 9/20 0.42
CA1 P00915 4/20 0.42
CA12 O43570 3/20 0.42
CA4 P22748 3/20 0.42
CA6 P23280 3/20 0.42
CA5A P35218 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA5B Q9Y2D0 3/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2D6 P10635 2/20 0.38
F2 P00734 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968190 0.98 LMNA (0.48) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL314445 0.98 LMNA (0.48) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL5368246 0.88 CA2 (0.46) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL4240715 0.86 CA2 (0.47) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL11583429 0.84 LMNA (0.56) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL2881344 0.83 LMNA (0.50) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL8464844 0.81 CA2 (0.64) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL819787 0.80 LMNA (0.52) LMNATSHRALDH1A1NT5ETDP1
SCHEMBL8083823 0.80 HTR6 (0.53) LMNATSHRALDH1A1TDP1SMN1; SMN2
SCHEMBL30446884 0.80 CA2 (0.57) LMNATSHRALDH1A1NT5ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505713-B2 High-purity sodium p-styrenesulfonate with excellent hue, method for producing the same, poly(sodium p-styrenesulfonate) with excellent hue using the same, and dispersant and synthetic starch for clothing finishing using the poly(sodium p-styrenesulfonate) TOSOH ORGANIC CHEMICAL CO., LTD (JP) 2016-11-29 US claimed
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) TOSOH ORGANIC CHEMICAL CO., LTD. (JP) 2015-09-03 US claimed
CN-118289795-A Surface modified barite powder and preparation method and application thereof 旬阳市健平矿业有限公司 2024-07-05 CN disclosed
CN-117209760-B Sulfonated benzimidazole polymer and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2024-03-12 CN disclosed
CN-117209760-A Sulfonated benzimidazole polymer and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2023-12-12 CN disclosed
CN-111269710-B Mobile terminal, shell component, electrochromic material and preparation method thereof 宁波祢若电子科技有限公司 2022-05-20 CN disclosed
US-11180657-B2 Polysulfonated fluorescence dyes ATTO-TEC GMBH (DE) 2021-11-23 US disclosed
CN-111269710-A Mobile terminal, shell component, electrochromic material and preparation method thereof 宁波祢若电子科技有限公司 2020-06-12 CN disclosed
US-20190322870-A2 NOVEL POLYSULFONATED FLUORESCENCE DYES ATTO-TEC GMBH (DE) 2019-10-24 US disclosed
US-20190100653-A1 NOVEL POLYSULFONATED FLUORESCENCE DYES ATTO-TEC GMBH (DE) 2019-04-04 US disclosed
US-9505713-B2 High-purity sodium p-styrenesulfonate with excellent hue, method for producing the same, poly(sodium p-styrenesulfonate) with excellent hue using the same, and dispersant and synthetic starch for clothing finishing using the poly(sodium p-styrenesulfonate) TOSOH ORGANIC CHEMICAL CO., LTD (JP) 2016-11-29 US disclosed
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) TOSOH ORGANIC CHEMICAL CO., LTD. (JP) 2015-09-03 US disclosed
CN-101098910-B Polybenzazole block copolymer SOLVAY 2011-04-13 CN disclosed
CN-101098910-A Polybenzazole block copolymer SOLVAY (BE) 2008-01-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11180657-B2 Polysulfonated fluorescence dyes CD44, ARSA, STS LMNA 3435/4885TSHR 4164/4885ALDH1A1 199/4885
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) HPSE, STS, TST LMNA 2070/4885TSHR 2827/4885ALDH1A1 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.