SCHEMBL1704532

SCHEMBL1704532

NC(=O)CCCN1C(=O)C=CC1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.62
FAAH O00519 5/20 0.62
PTGS1 P23219 7/20 0.60
PTGS2 P35354 7/20 0.60
ALDH1A1 P00352 3/20 0.60
LMNA P02545 2/20 0.60
MAPT P10636 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
HPGD P15428 2/20 0.60
HSP90AA1 P07900 1/20 0.60
TLR9 Q9NR96 1/20 0.60
TP53 P04637 1/20 0.60
PKM P14618 1/20 0.60
XBP1 P17861 1/20 0.60
MAPK1 P28482 1/20 0.60
HTT P42858 1/20 0.60
RECQL P46063 1/20 0.60
RAB9A P51151 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
GPR35 Q9HC97 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22398888 0.94 PTGS1 (0.69) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL30180925 0.92 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL19817136 0.92 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL1887612 0.92 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL28698933 0.92 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL255340 0.89 MGLL (0.52) MGLLFAAHPTGS1PTGS2ALDH1A1
Ethylene Glycol SCHEMBL2193141 0.83 PTGS1 (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
Ethylene Glycol SCHEMBL1082278 0.83 PTGS1 (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL155346 0.83 PTGS1 (0.85) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL1965501 0.83 MGLL (0.62) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7737251-B2 Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2010-06-15 US claimed
EP-2114437-A2 MODIFIED CORTICOTROPIN RELEASING FACTOR PEPTIDES AND USES THEREOF ConjuChem Biotechnologies Inc. (CA) 2009-11-11 EP claimed
US-20090054332-A1 THOMBOPOIETIN PEPTIDE CONJUGATES CONJUCHEM BIOTECHNOLOGIES, INC. (CA) 2009-02-26 US claimed
WO-2008157824-A2 THROMBOPOIETIN PEPTIDE CONJUGATES CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2008-12-24 WO claimed
CN-101289500-A Long lasting fusion peptide inhibitor of viral infection CONJUCHEM BIOTECHNOLOGIES INC (CA) 2008-10-22 CN claimed
EP-1980572-A1 Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders ConjuChem Biotechnologies Inc. (CA) 2008-10-15 EP claimed
US-20080167231-A1 Modified Corticotropin Releasing Factor Peptides and Uses Thereof CONJUCHEM BIOTECHNOLOGIES INC. 2008-07-10 US claimed
WO-2008047241-A2 MODIFIED CORTICOTROPIN RELEASING FACTOR PEPTIDES AND USES THEREOF CONJUCHEM BIOTECHNOLOGIES INC. (US) 2008-04-24 WO claimed
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 US disclosed
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-19 US disclosed
US-20250186627-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-12 US disclosed
US-20250161501-A1 Radiolabeled Compounds for Imaging of Fibroblast Activation Protein (FAP) and Treatment of FAP-Related Disorders PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-05-22 US disclosed
WO-2025054727-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-03-20 WO disclosed
US-12246076-B2 Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-03-11 US disclosed
WO-2003005026-A2 CHEMICAL CAPTURE REAGENT AMERSHAM BIOSCIENCES UK LIMITED (GB) 2003-01-16 WO disclosed
WO-2002066511-A2 LONG LASTING GLUCAGON-LIKE PEPTIDE 2 (GLP-2) FOR THE TREATMENT OF GASTROINTESTINAL DISEASES AND DISORDERS CONJUCHEM INC. (CA) 2002-08-29 WO disclosed
WO-2002062844-A2 LONG LASTING GROWTH HORMONE RELEASING FACTOR DERIVATIVES CONJUCHEM INC. (CA) 2002-08-15 WO disclosed
CN-1351611-A Long-acting Fusion Peptide Inhibitors of Viral Infection CONJUCHEM INC (CA) 2002-05-29 CN disclosed
EP-1042003-A1 DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO Conjuchem, Inc. (CA) 2000-10-11 EP disclosed
WO-1999048536-A2 DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO CONJUCHEM, INC. (CA) 1999-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186627-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN FSHR, ESRRA, ESRRG MGLL 4201/4885FAAH 3570/4885PTGS1 4532/4885
US-20250161501-A1 Radiolabeled Compounds for Imaging of Fibroblast Activation Protein (FAP) and Treatment of FAP-Related Disorders FAP, FIBP, FGFR1 MGLL 3061/4885FAAH 39/4885PTGS1 3440/4885
US-12246076-B2 Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders GRPR, NPY5R, NPY2R MGLL 3505/4885FAAH 814/4885PTGS1 2081/4885
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R MGLL 3330/4885FAAH 636/4885PTGS1 2040/4885
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF GRPR, GIPR, GLP1R MGLL 1847/4885FAAH 874/4885PTGS1 1358/4885
US-20090054332-A1 THOMBOPOIETIN PEPTIDE CONJUGATES TEK, MPL, PTMS MGLL 4269/4885FAAH 2922/4885PTGS1 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.