SCHEMBL17045943

SCHEMBL17045943

CCN([SiH2]c1ccccc1)C1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 4/20 0.38
USP2 O75604 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
G6PC1 P35575 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
CYP2C19 P33261 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
MITF O75030 1/20 0.35
RAB9A P51151 1/20 0.35
PAX8 Q06710 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17046015 0.98 L3MBTL1 (0.44) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17046168 0.86 DRD3 (0.40) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17046108 0.84 L3MBTL1 (0.39) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17046201 0.75 KDM4E (0.44) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17045957 0.73 ALDH1A1 (0.47) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL19149950 0.73 L3MBTL1 (0.41) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17046232 0.73 L3MBTL1 (0.35) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17046249 0.72 KDM4E (0.42) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL17046064 0.72 KDM4E (0.42) L3MBTL1KDM4EUSP2HPGDHSD17B10
SCHEMBL19148907 0.71 L3MBTL1 (0.43) L3MBTL1KDM4EUSP2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294250-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2019-05-21 US disclosed
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-9758534-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2017-09-12 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
EP-2913334-A1 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT L3MBTL1 471/4885KDM4E 2506/4885USP2 1680/4885
US-20170204120-A1 Organoaminosilanes and Methods for Making Same DDAH1, IDUA, DDT L3MBTL1 471/4885KDM4E 2506/4885USP2 1680/4885
US-10294250-B2 Organoaminosilanes and methods for making same DDAH1, IDUA, DDT L3MBTL1 471/4885KDM4E 2506/4885USP2 1680/4885
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT L3MBTL1 471/4885KDM4E 2506/4885USP2 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.