Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438858 | 1.00 | PDE4A (0.52) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL1062215 | 1.00 | PDE4A (0.52) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL8658675 | 0.98 | PDE4A (0.50) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| Bicarbonate SCHEMBL30050792 | 0.96 | PDE4A (0.53) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL28292381 | 0.94 | PDE4A (0.43) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL858818 | 0.94 | PDE4A (0.43) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL18825591 | 0.94 | PDE4A (0.43) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL1843798 | 0.94 | PDE4A (0.43) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| Acrylamide SCHEMBL6682076 | 0.91 | PDE4A (0.44) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL28096121 | 0.83 | PDE4A (0.38) | PDE4ALMNAUSP2SLCO1B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552183-B2 | Process for the covalent coupling of two molecules by means of a diels-alder reaction with inverse electron requirement | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2013-10-08 | — | — | US | claimed |
| US-20100016545-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2010-01-21 | — | — | US | claimed |
| EP-2044035-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts (DE) | 2009-04-08 | — | — | EP | claimed |
| WO-2007144200-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-21 | — | — | WO | claimed |
| EP-1867638-A1 | Procedure for the Conection of two Molecules via Diels-Alder Reactions with Inverse Electron Demand | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-19 | — | — | EP | claimed |
| CN-115043890-B | Synthesis method of allyl glucoside | 河北科技大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-106659915-B | Skin care compositions | 博姿有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-106456527-A | Water-in-oil emulsion for skin care | 博姿有限公司 | 2017-02-22 | — | — | CN | disclosed |
| US-8993537-B2 | Forming porous scaffold from cellulose derivatives | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-03-31 | — | — | US | disclosed |
| US-20130274440-A1 | DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2013-10-17 | — | — | US | disclosed |
| US-8552183-B2 | Process for the covalent coupling of two molecules by means of a diels-alder reaction with inverse electron requirement | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2013-10-08 | — | — | US | disclosed |
| US-20130005945-A1 | FORMING POROUS SCAFFOLD FROM CELLULOSE DERIVATIVES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2013-01-03 | — | — | US | disclosed |
| US-6235720-B1 | DRUG; MICROBIOCIDE, VIRICIDE, BACTERICIDE, ANTIPROTOZOA AGENT | GELTEX PHARMACEUTICALS, INC. | 2001-05-22 | — | — | US | disclosed |
| WO-2000078844-A1 | MULTIFUNCTIONAL NONIONIC SILOXANE COPOLYMER FOR MODIFICATION OF SYNTHETIC MATERIALS | EURO MANAGEMENT & TRUST COMPANY ESTABLISHMENT (US) | 2000-12-28 | — | — | WO | disclosed |
| US-5939537-A | Acid-functionalized saccharide monomers | GELTEX PHARMACEUTICALS INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0929562-A1 | ACID-FUNCTIONALIZED SACCHARIDES AS POLYVALENT ANTI-INFECTIVES | GELTEX PHARMACEUTICALS, INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5821312-A | Acid-functionalized saccharides as polyvalent anti-infectives | GELTEX PHARMACEUTICALS, INC. (US) | 1998-10-13 | — | — | US | disclosed |
| WO-1998012203-A1 | ACID-FUNCTIONALIZED SACCHARIDES AS POLYVALENT ANTI-INFECTIVES | GELTEX PHARMACEUTICALS, INC. (US) | 1998-03-26 | — | — | WO | disclosed |
| US-5700458-A | Acid-functionalized saccharides as polyvalent anti-infectives | GELTEX PHARMACEUTICALS INC. (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0080855-A2 | Compounds and compositions for oil recovery | The British Petroleum Company p.l.c. (GB) | 1983-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274440-A1 | DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | IAPP, NPPA, ANXA6 | PDE4A 2665/4885LMNA 528/4885L3MBTL1 3506/4885 |
| US-20100016545-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | CX3CR1, NR3C2, NR4A2 | PDE4A 4204/4885LMNA 4669/4885L3MBTL1 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.