SCHEMBL17047634

SCHEMBL17047634

CCOC(=O)CCP(=O)(CCC(C)Br)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TRPA1 O75762 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 2/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
LPAR6 P43657 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR4 Q99677 1/20 0.32
LPAR5 Q9H1C0 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
ENPP2 Q13822 1/20 0.32
SMYD3 Q9H7B4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905595 0.88 ALOX15 (0.38) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL18911237 0.85 ALOX15 (0.36) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL17047635 0.81 ALOX15 (0.41) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL8231853 0.81 ALDH1A1 (0.44) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL18905592 0.80 CYP1A2 (0.41) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL17047631 0.80 ALOX15 (0.34) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL17072529 0.80 ALDH1A1 (0.42) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL15743383 0.80 ALDH1A1 (0.42) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL2354099 0.79 CYP1A2 (0.42) ALOX15SMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL1206813 0.76 L3MBTL1 (0.50) L3MBTL1POLBALDH1A1TRPA1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122757-B1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO LTD (CN) 2023-09-06 EP disclosed
US-10696700-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US disclosed
US-10696699-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US disclosed
US-10696699-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US disclosed
US-10696700-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US disclosed
US-10683314-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-16 US disclosed
US-10683314-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-16 US disclosed
US-10464955-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-11-05 US disclosed
US-10464955-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-11-05 US disclosed
US-20190127401-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-02 US disclosed
US-20190127399-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-02 US disclosed
US-20190127399-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-02 US disclosed
US-20190127401-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-02 US disclosed
US-20190127400-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-02 US disclosed
US-20170152274-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2017-06-01 US disclosed
US-20170152274-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2017-06-01 US disclosed
US-20170152274-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD. (CN) 2017-06-01 US disclosed
EP-3122757-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION Hangzhou Dac Biotech Co., Ltd (CN) 2017-02-01 EP disclosed
WO-2015127685-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD (CN) 2015-09-03 WO disclosed
WO-2015127685-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO., LTD (CN) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152274-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-20190127399-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-10696700-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-10464955-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-20190127401-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-20190127400-A1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-10683314-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885
US-10696699-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 ALOX15 4573/4885SMN1; SMN2 3710/4885L3MBTL1 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.