SCHEMBL1704808

SCHEMBL1704808

CCCCC(C(=O)NN)N1C(=O)C=CC1=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
L3MBTL1 Q9Y468 1/20 0.36
PTGS1 P23219 3/20 0.35
PTGS2 P35354 3/20 0.35
MGLL Q99685 2/20 0.35
FAAH O00519 1/20 0.35
DPP7 Q9UHL4 5/20 0.35
SLC15A1 P46059 1/20 0.35
POLB P06746 1/20 0.33
CHEK1 O14757 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
DPP8 Q6V1X1 4/20 0.33
DPP4 P27487 3/20 0.33
DPP9 Q86TI2 3/20 0.33
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15021865 0.98 CA1 (0.46) CA1CA2L3MBTL1PTGS1PTGS2
SCHEMBL20377214 0.94 CA1 (0.41) CA1CA2PTGS1PTGS2MGLL
Trifluoroacetic Acid SCHEMBL30150804 0.91 CA1 (0.40) CA1CA2L3MBTL1
SCHEMBL30153762 0.90 CA1 (0.39) CA1CA2MGLLSIGMAR1
SCHEMBL10182253 0.84 PTGS1 (0.35) CA1CA2PTGS1PTGS2MGLL
SCHEMBL2219783 0.82 CA2 (0.43) CA1CA2L3MBTL1PTGS1PTGS2
SCHEMBL43970 0.80 PTPN1 (0.42) CA2PTGS1PTGS2MGLLFAAH
SCHEMBL12094816 0.80 MGLL (0.39) CA1CA2PTGS1PTGS2MGLL
SCHEMBL5165799 0.79 CA2 (0.46) CA1CA2L3MBTL1PTGS1PTGS2
SCHEMBL12409955 0.79 POLB (0.36) DPP7SLC15A1POLBDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024091979-A1 CD276 (B7-H3) ANTIBODY-DRUG CONJUGATES BRICKBIO, INC. (US) 2024-05-02 WO claimed
EP-4171644-A2 SAPONIN DERIVATIVES FOR USE IN MEDICINE Sapreme Technologies B.V. (NL) 2023-05-03 EP claimed
EP-4171639-A2 SAPONIN DERIVATIVES FOR USE IN MEDICINE Sapreme Technologies B.V. (NL) 2023-05-03 EP claimed
EP-4171643-A1 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF Sapreme Technologies B.V. (NL) 2023-05-03 EP claimed
CN-115568232-A Tin-based perovskite solar cell with tin-based perovskite thin film subjected to surface treatment by multifunctional ionic salt and preparation method of tin-based perovskite solar cell 山东大学 2023-01-03 CN claimed
EP-4003425-A2 BIOACTIVE SAPONIN LINKED TO A FUNCTIONAL MOIETY SAPREME TECHNOLOGIES B.V. (NL) 2022-06-01 EP claimed
EP-4003427-A1 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2022-06-01 EP claimed
WO-2021261998-A1 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF SAPREME TECHNOLOGIES B.V. (NL) 2021-12-30 WO claimed
WO-2021260054-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2021-12-30 WO claimed
WO-2021260061-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2021-12-30 WO claimed
US-8420802-B2 Polymer support UNIVERSITY OF CAPE TOWN (ZA) 2013-04-16 US claimed
EP-2478049-A1 A POLYMER SUPPORT University of Cape Town (ZA) 2012-07-25 EP claimed
US-20120178916-A1 Polymer Support UNIVERSITY OF CAPE TOWN (ZA) 2012-07-12 US claimed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO claimed
US-20110142762-A1 Conjugates for medical imaging comprising carrier, targeting moiety and a contrast agent NOVOZYMES BIOPHARMA DK A/S (DK) 2011-06-16 US claimed
EP-1605979-B1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT UPPERTON LTD (GB) 2008-10-22 EP claimed
JP-2006518727-A 2006-08-17 JP claimed
US-20060171892-A1 Conjugates for medical imaging comprising carrier, targetting moiety and a contrast agent NOVOZYMES BIOPHARMA UK LIMITED (GB) 2006-08-03 US claimed
EP-1605979-A1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT Upperton Limited (GB) 2005-12-21 EP claimed
WO-2004071536-A1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT UPPERTON LIMITED (GB) 2004-08-26 WO claimed