Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704808 | 0.84 | CA1 (0.47) | PTGS1PTGS2MGLLFAAHDPP7 | |
| Hydrochloric Acid SCHEMBL15021865 | 0.83 | CA1 (0.46) | PTGS1PTGS2MGLLFAAHDPP7 | |
| SCHEMBL20887626 | 0.81 | PKM (0.33) | MGLL | |
| SCHEMBL12094816 | 0.80 | MGLL (0.39) | PTGS1PTGS2MGLLFAAHCA1 | |
| SCHEMBL43970 | 0.80 | PTPN1 (0.42) | PTGS1PTGS2MGLLFAAHCA2 | |
| SCHEMBL5165799 | 0.79 | CA2 (0.46) | PTGS1PTGS2MGLLFAAHCA1 | |
| SCHEMBL20377214 | 0.79 | CA1 (0.41) | PTGS1PTGS2MGLLFAAHCA1 | |
| SCHEMBL2034675 | 0.79 | MGLL (0.38) | PTGS1PTGS2MGLLFAAHCA1 | |
| Hydrochloric Acid SCHEMBL4277446 | 0.79 | PTPN1 (0.41) | PTGS1PTGS2MGLLFAAHCA2 | |
| SCHEMBL2219783 | 0.79 | CA2 (0.43) | PTGS1PTGS2MGLLFAAHCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |