Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17110215 | 0.84 | SERPINA6 (0.34) | MMP2MAPT | |
| SCHEMBL1141761 | 0.77 | TLR4 (0.49) | MAPT | |
| SCHEMBL24249958 | 0.77 | TLR4 (0.49) | MAPT | |
| SCHEMBL7928906 | 0.74 | ALDH1A1 (0.37) | SIRT1MAPTMCL1 | |
| SCHEMBL3989012 | 0.72 | — | — | |
| SCHEMBL3989017 | 0.72 | — | — | |
| SCHEMBL11618738 | 0.68 | PGR (0.32) | — | |
| SCHEMBL11624889 | 0.67 | HSD17B10 (0.38) | MAPT | |
| SCHEMBL29165336 | 0.67 | TLR4 (0.34) | MAPT | |
| SCHEMBL11351771 | 0.67 | APLNR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |