Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644165 | 0.85 | SLC6A3 (0.38) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL7633659 | 0.81 | MEN1 (0.46) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL11624889 | 0.81 | HSD17B10 (0.38) | ALDH1A1KDM4EMAPTESR2SMN1; SMN2 | |
| SCHEMBL17048600 | 0.74 | MMP2 (0.33) | SIRT1MAPTMCL1 | |
| SCHEMBL7640072 | 0.74 | CHRM2 (0.47) | ALDH1A1MAPTKMT2AHSD17B10CFTR | |
| SCHEMBL7634605 | 0.73 | CHRM2 (0.50) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL7642686 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL11621033 | 0.69 | CHRM2 (0.39) | ALDH1A1KDM4EKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7643676 | 0.67 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL11642020 | 0.65 | SMN1; SMN2 (0.46) | ALDH1A1S1PR1S1PR5KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020112-A1 | Process for preparing (hetero) aromatic substituted benzene derivatives | TOYA TETSUYA (JP) | 2001-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020112-A1 | Process for preparing (hetero) aromatic substituted benzene derivatives | AHR, CYP3A4, CYP4B1 | ALDH1A1 1596/4885S1PR1 4270/4885S1PR5 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.