Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048714 | 0.85 | MAPT (0.39) | GSRALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL17048849 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL17048875 | 0.80 | GPR35 (0.36) | ALDH1A1MAPTHTTTSHR | |
| SCHEMBL17048896 | 0.80 | USP7 (0.33) | ALDH1A1MAPK1LMNAHTTUSP7 | |
| SCHEMBL17048815 | 0.78 | TDP1 (0.33) | TDP1 | |
| SCHEMBL4851936 | 0.76 | ALDH1A1 (0.47) | CNR1GSRALDH1A1MAPTMAPK1 | |
| SCHEMBL17048823 | 0.76 | HSD17B10 (0.32) | ALDH1A1MAPTMAPK1SMN1; SMN2HTT | |
| SCHEMBL17048987 | 0.73 | MEN1 (0.38) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL17048785 | 0.73 | CNR1 (0.32) | HSP90AA1CNR1SMN1; SMN2LMNAHTT | |
| SCHEMBL3336779 | 0.71 | GSR (0.55) | CNR1GSRALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |