Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048685 | 0.78 | CNR1 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL17048896 | 0.75 | USP7 (0.33) | LMNAALDH1A1HTT | |
| SCHEMBL17048826 | 0.73 | HSP90AA1 (0.38) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL202480 | 0.70 | MEN1 (0.45) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL17048798 | 0.70 | MALT1 (0.34) | MEN1KMT2APOLBMALT1NPC1 | |
| SCHEMBL17048875 | 0.65 | GPR35 (0.36) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL17048849 | 0.65 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL844114 | 0.65 | MAOA (0.47) | ALDH1A1POLBERN1KDM4EGPR3 | |
| SCHEMBL17048799 | 0.64 | MEN1 (0.33) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL202663 | 0.64 | POLB (0.51) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |