Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048778 | 0.86 | DNM1 (0.30) | DNM1 | |
| SCHEMBL11418131 | 0.86 | DNM1 (0.37) | DNM1 | |
| SCHEMBL10498368 | 0.86 | DNM1 (0.46) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL13326798 | 0.84 | DNM1 (0.45) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL8202515 | 0.84 | DNM1 (0.45) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL9118432 | 0.83 | DNM1 (0.38) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL5107774 | 0.83 | DNM1 (0.41) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL3817432 | 0.82 | DNM1 (0.50) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL27759847 | 0.80 | DNM1 (0.48) | DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL8778602 | 0.80 | DNM1 (0.48) | DNM1ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150266824-A1 | Pyrazole Amide Derivative | TEIJIN LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266824-A1 | Pyrazole Amide Derivative | RORC, RORB, RORA | DNM1 3983/4885ALDH1A1 923/4885CNR1 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.