Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SDCBP | O00560 | 1/20 | 0.48 |
| ▸ | SDC2 | P34741 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049337 | 1.00 | LMNA (0.53) | LMNAKMT2APOLBMAPTNPSR1 | |
| SCHEMBL17049356 | 0.87 | ALDH1A1 (0.66) | KMT2APOLBMAPTNPSR1ALDH1A1 | |
| SCHEMBL17049355 | 0.87 | ALDH1A1 (0.66) | KMT2APOLBMAPTNPSR1ALDH1A1 | |
| SCHEMBL17049289 | 0.85 | ALDH1A1 (0.56) | KMT2APOLBMAPTNPSR1ALDH1A1 | |
| SCHEMBL17049347 | 0.77 | ALDH1A1 (0.52) | KMT2APOLBMAPTNPSR1ALDH1A1 | |
| SCHEMBL17049345 | 0.77 | ALDH1A1 (0.52) | KMT2APOLBMAPTNPSR1ALDH1A1 | |
| SCHEMBL25252329 | 0.76 | L3MBTL1 (0.56) | KMT2APOLBALDH1A1MEN1L3MBTL1 | |
| SCHEMBL25252331 | 0.76 | L3MBTL1 (0.56) | KMT2APOLBALDH1A1MEN1L3MBTL1 | |
| SCHEMBL17049327 | 0.76 | ALDH1A1 (0.45) | KMT2APOLBALDH1A1MEN1L3MBTL1 | |
| SCHEMBL17049330 | 0.76 | ALDH1A1 (0.45) | KMT2APOLBALDH1A1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015131100-A1 | LIGAND-CONTROLLED C(SP3)-H ARYLATION AND OLEFINATION IN SYNTHESIS OF UNNATURAL CHIRAL ALPHA AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-09-03 | — | — | WO | disclosed |