Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049345 | 1.00 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL17049355 | 0.87 | ALDH1A1 (0.66) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL17049356 | 0.87 | ALDH1A1 (0.66) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL25252329 | 0.85 | L3MBTL1 (0.56) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL25252331 | 0.85 | L3MBTL1 (0.56) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL30229450 | 0.81 | SLC7A5 (0.53) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL17049289 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL17049339 | 0.77 | LMNA (0.53) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL17049337 | 0.77 | LMNA (0.53) | ALDH1A1GAAPOLBL3MBTL1KMT2A | |
| SCHEMBL17049334 | 0.77 | MEN1 (0.47) | ALDH1A1GAAPOLBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015131100-A1 | LIGAND-CONTROLLED C(SP3)-H ARYLATION AND OLEFINATION IN SYNTHESIS OF UNNATURAL CHIRAL ALPHA AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-09-03 | — | — | WO | disclosed |