SCHEMBL1704973

SCHEMBL1704973

Nc1ccc(C2CCCN(c3ccc(N)cc3)CC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 3/20 0.56
GAA P10253 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
HTT P42858 2/20 0.56
KMT2A Q03164 2/20 0.56
THRB P10828 2/20 0.56
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
USP2 O75604 1/20 0.56
TP53 P04637 1/20 0.56
POLB P06746 1/20 0.56
ALOX15 P16050 1/20 0.56
RECQL P46063 1/20 0.56
RAB9A P51151 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HSD17B10 Q99714 1/20 0.56
SLC18A3 Q16572 1/20 0.50
GFER P55789 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29449720 0.93 MAPT (0.53) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL10035921 0.85 MAPT (0.49) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL241159 0.84 DHFR (0.50) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL16763481 0.84 SLC18A3 (0.47) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL20401806 0.82 MAPT (0.46) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL9828388 0.81 CHKA (0.48) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL2756339 0.79 MAPT (0.46) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL23064493 0.79 L3MBTL1 (0.52) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL31224935 0.79 FFAR4 (0.56) MAPTALDH1A1KDM4EGAAL3MBTL1
SCHEMBL6221489 0.79 MAPT (0.60) MAPTALDH1A1KDM4EGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453477-B1 DEVELOPER-COUPLER COMBINATION CONTAINING 2,4-DICHLORO-3-AMINOPHENOL HENKEL KGAA (DE) 2007-10-17 EP claimed
EP-1453476-B1 NOVEL OXIDATION DYES COMPRISING 2,4-DICHLORO-3-AMINOPHENOL HENKEL KGAA (DE) 2006-05-03 EP claimed
EP-1301163-B1 OXIDATIVE HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2,4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT HENKEL KGAA (DE) 2005-01-26 EP claimed
EP-1453476-A1 NOVEL OXIDATION DYES COMPRISING 2,4-DICHLORO-3-AMINOPHENOL Henkel Kommanditgesellschaft auf Aktien (DE) 2004-09-08 EP claimed
WO-2003053385-A1 NOVEL OXIDATION DYES COMPRISING 2,4-DICHLORO-3-AMINOPHENOL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-07-03 WO claimed
US-20030106167-A1 Oxidation colorant of a m-phenylenediamine and a primary intermediates of a p-phenylenediamine, a p-aminophenol binuclear primary and intermediates or pyrazole derivatives HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-06-12 US claimed
EP-1235550-A2 NEW COLOURING COMBINATION Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-04 EP claimed
WO-2002026202-A2 OXIDATION DYES WITH 2-AMINO-5-METHYLPHENOL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-04 WO claimed
WO-2001041717-A2 NEW COLOURING COMBINATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-14 WO claimed
EP-3998059-A9 MILD PREPARATIONS AS CLEANING OR CARE COMPOSITIONS FOR REMOVING CARBOHYDRATES OR STAINS Perfect Ideas GmbH (CH) 2022-09-28 EP disclosed
EP-3998059-A1 MILD PREPARATIONS AS CLEANING OR CARE COMPOSITIONS FOR REMOVING CARBOHYDRATES OR STAINS Perfect Ideas GmbH (CH) 2022-05-18 EP disclosed
EP-3290020-B1 MILD PREPARATIONS CONTAINING ALKOXYLATED FATTY ACID AMIDES PERFECT IDEAS GMBH (CH) 2021-11-24 EP disclosed
EP-3290020-A1 MILD PREPARATIONS CONTAINING ALKOXYLATED FATTY ACID AMIDES Richli, Remo (CH) 2018-03-07 EP disclosed
EP-1761232-B2 HAIR CLEANING AGENTS CONTAINING AMINO-FUNCTIONAL SILICONES HENKEL AG & CO KGAA (DE) 2015-12-16 EP disclosed
EP-0885607-A2 Neutral brightening and emulsifying composition for treating hair or fibres Henkel Kommanditgesellschaft auf Aktien (DE) 1998-12-23 EP disclosed
EP-0873987-A1 Prefluoroacylated 3-Aminophenol derivatives and their use as hair dyeing agents Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP disclosed
EP-0873746-A2 Dyestuff for keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP disclosed
EP-0873743-A2 Use of benzylidene-ketones for dyeing keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP disclosed
EP-0873744-A2 Use of heterocyclic carbonyl compounds for dying keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP disclosed
EP-0873745-A2 Dyestuff for keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030106167-A1 Oxidation colorant of a m-phenylenediamine and a primary intermediates of a p-phenylenediamine, a p-aminophenol binuclear primary and intermediates or pyrazole derivatives KRT18, PPOX, CDC73 MAPT 378/4885ALDH1A1 725/4885KDM4E 2268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.