SCHEMBL17049867

SCHEMBL17049867

CC1C(C)C(C)C(c2cccc3c2N(C)C(C)CC3)C1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
CYP1A2 P05177 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
CYP2C19 P33261 1/20 0.38
HBB P68871 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SRD5A1 P18405 3/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HTR1A P08908 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17049866 0.80 SRD5A1 (0.41) SRD5A1HTR1ASIGMAR1PDPK1
SCHEMBL18973672 0.76 MAPT (0.37) MAPTMEN1CYP1A2KMT2ALMNA
SCHEMBL6578810 0.76 HTR1A (0.44) HTR1A
SCHEMBL25093088 0.75 L3MBTL1 (0.34) MAPTMEN1CYP1A2KMT2ALMNA
SCHEMBL10840651 0.70 HTR2C (0.42) MAPTMEN1CYP1A2KMT2ALMNA
SCHEMBL7421714 0.70 ESR1 (0.39) MAPTMEN1CYP1A2KMT2ALMNA
SCHEMBL811848 0.67 POLB (0.51) MEN1KMT2AL3MBTL1SRD5A1
SCHEMBL15222054 0.67 POLB (0.51) MEN1KMT2AL3MBTL1SRD5A1
SCHEMBL9230128 0.67 POLB (0.51) MEN1KMT2AL3MBTL1SRD5A1
SCHEMBL29659945 0.67 POLB (0.51) MEN1KMT2AL3MBTL1SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9120836-B2 Method for preparing transition metal complexes, transition metal complexes prepared using the method, catalyst composition containing the complexes LG CHEM, LTD. (KR) 2015-09-01 US disclosed