Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17050384 | 0.89 | KDM4E (0.37) | APPCREBBPMEN1KMT2AALDH1A1 | |
| SCHEMBL17052075 | 0.86 | APP (0.35) | APPMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL79148 | 0.77 | HPGD (0.37) | APPMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL79150 | 0.77 | HPGD (0.37) | APPMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL79149 | 0.77 | HPGD (0.37) | APPMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30057466 | 0.67 | FDPS (0.62) | ALDH1A1PDE4BFDPSMAPT | |
| SCHEMBL22369978 | 0.67 | FDPS (0.62) | ALDH1A1PDE4BFDPSMAPT | |
| SCHEMBL19304004 | 0.66 | KDM4E (0.54) | APPMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL29503029 | 0.65 | NFE2L2 (0.62) | APPCREBBPMEN1KMT2AALDH1A1 | |
| SCHEMBL26669477 | 0.65 | NFE2L2 (0.62) | APPCREBBPMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | ACSS2, ACACB, ACAT2 | APP 2384/4885CREBBP 1324/4885MEN1 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.