Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.76 |
| ▸ | PPARG | P37231 | 2/20 | 0.69 |
| ▸ | CTSS | P25774 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | KLK7 | P49862 | 2/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | CDC25B | P30305 | 4/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.49 |
| ▸ | CDC25A | P30304 | 2/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825297 | 0.91 | PPARA (0.63) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL17051 | 0.91 | PPARA (0.90) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL1132901 | 0.91 | PPARA (0.90) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL828674 | 0.91 | PPARA (0.90) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL29135753 | 0.86 | PPARA (0.75) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL29556874 | 0.86 | PPARA (0.75) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL20899650 | 0.86 | PPARA (0.82) | PPARAPPARGCTSSRAB9ACTSL | |
| SCHEMBL12130757 | 0.86 | PPARA (0.85) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL3817194 | 0.85 | CTSS (0.61) | PPARAPPARGCTSSCTSLCTSB | |
| SCHEMBL3820452 | 0.85 | CTSS (0.61) | PPARAPPARGCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-20050075281-A1 | peptide antibiotics comprising lysobactin derivatives used for treatment and/or prophylaxis of bacterial infectious diseases; cyclic peptides | BAYER HEALTHCARE AG (DE) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075281-A1 | peptide antibiotics comprising lysobactin derivatives used for treatment and/or prophylaxis of bacterial infectious diseases; cyclic peptides | VIP, LNPEP, HAMP | PPARA 808/4885PPARG 2346/4885CTSS 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.