SCHEMBL17059018

SCHEMBL17059018

Cc1ccc(C)c(-c2nc3ccccc3n2C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.56
RAB9A P51151 9/20 0.56
SMN1; SMN2 Q16637 7/20 0.56
MAPT P10636 4/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 7/20 0.51
ALDH1A1 P00352 7/20 0.50
PKM P14618 4/20 0.50
TP53 P04637 4/20 0.50
GAA P10253 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ALOX15 P16050 1/20 0.50
HPGD P15428 5/20 0.49
LMNA P02545 2/20 0.49
GFER P55789 2/20 0.48
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20867465 0.84 RAB9A (0.53) NPC1RAB9ASMN1; SMN2MAPTTDP1
SCHEMBL12648806 0.83 MEN1 (0.57) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL23749248 0.80 KDM4E (0.48) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL30865864 0.80 KDM4E (0.48) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL16692191 0.80 KDM4E (0.64) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL26027020 0.79 RAB9A (0.44) NPC1RAB9ASMN1; SMN2MAPTTDP1
SCHEMBL1171430 0.78 MEN1 (0.69) NPC1RAB9ASMN1; SMN2MAPTTDP1
SCHEMBL14699735 0.78 AGPAT2 (0.49) NPC1RAB9ASMN1; SMN2MAPTTDP1
SCHEMBL16552965 0.77 MEN1 (0.54) NPC1RAB9ASMN1; SMN2MAPTTDP1
SCHEMBL15177867 0.77 MEN1 (0.63) NPC1RAB9ASMN1; SMN2MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500790-B2 Optical film, circularly polarizing plate, and image display device Konica Minolta, Inc. (JP) 2016-11-22 US disclosed
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE SUN2, HTR3D, CRY1 NPC1 1653/4885RAB9A 2452/4885SMN1; SMN2 1468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.