SCHEMBL14699735

SCHEMBL14699735

Cc1ccc2c(c1)nc(-c1cc(C)c(-c3nc4cc(C)ccc4n3C)cc1C)n2C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGPAT2 O15120 1/20 0.49
KDM4E B2RXH2 2/20 0.48
HSD17B10 Q99714 1/20 0.48
ACSS2 Q9NR19 1/20 0.47
MEN1 O00255 1/20 0.44
NR1I2 O75469 1/20 0.44
AHR P35869 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
NLRP3 Q96P20 1/20 0.43
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
PIK3CG P48736 1/20 0.42
NQO2 P16083 1/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4399013 0.81 SMN1; SMN2 (0.49) AGPAT2KDM4EHSD17B10ACSS2MEN1
SCHEMBL17149164 0.79 HDAC1 (0.49) AGPAT2KDM4EHSD17B10ACSS2MEN1
SCHEMBL17059018 0.78 NPC1 (0.56) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL30195304 0.78 ALDH1A1 (0.52) KDM4EHSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL28886321 0.78 ALDH1A1 (0.52) KDM4EHSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL12354514 0.78 ACSS2 (0.47) AGPAT2KDM4EHSD17B10ACSS2MEN1
SCHEMBL1104834 0.77 NLRP3 (0.65) KDM4EHSD17B10ACSS2MEN1NR1I2
SCHEMBL1104855 0.77 RAB9A (0.59) KDM4EHSD17B10ACSS2MEN1KMT2A
SCHEMBL15426344 0.77 ACSS2 (0.46) AGPAT2KDM4EHSD17B10ACSS2MEN1
SCHEMBL10249140 0.76 MEN1 (0.66) AGPAT2KDM4EHSD17B10ACSS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2008318-B1 METHOD FOR PREPARING DOPED ORGANIC SEMICONDUCTOR MATERIALS NOVALED AG (DE) 2013-02-13 EP disclosed