SCHEMBL17059031

SCHEMBL17059031

Cc1ccc(C)c(-n2ccccc2=O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.49
ALDH1A1 P00352 6/20 0.46
MPI P34949 2/20 0.45
PHOSPHO1 Q8TCT1 2/20 0.45
PMM2 O15305 1/20 0.45
HCAR1 Q9BXC0 1/20 0.43
MAPT P10636 3/20 0.42
TP53 P04637 2/20 0.42
KDM4E B2RXH2 3/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
BLM P54132 1/20 0.41
LMNA P02545 4/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HTT P42858 3/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8306577 0.86 NPSR1 (0.47) HSD17B10ALDH1A1HCAR1MAPTTP53
SCHEMBL16104143 0.81 MGLL (0.48) ALDH1A1HCAR1MAPTKDM4EHPGD
SCHEMBL8306550 0.79 MAP3K5 (0.40) HSD17B10ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL8306979 0.79 METAP2 (0.48) HSD17B10ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL3349831 0.79 ALDH1A1 (0.36) HSD17B10ALDH1A1HCAR1MAPTTP53
SCHEMBL3310092 0.78 ALDH1A1 (0.52) HSD17B10ALDH1A1MPIPHOSPHO1PMM2
SCHEMBL9985608 0.78 MYC (0.43) HSD17B10ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL14502103 0.76 ALDH1A1 (0.36) HSD17B10ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL92819 0.75 KDM4E (0.57) HSD17B10ALDH1A1MPIPHOSPHO1PMM2
SCHEMBL17058996 0.75 CYP1A2 (0.42) HSD17B10ALDH1A1KDM4ECYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500790-B2 Optical film, circularly polarizing plate, and image display device Konica Minolta, Inc. (JP) 2016-11-22 US disclosed
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE SUN2, HTR3D, CRY1 HSD17B10 1335/4885ALDH1A1 1670/4885MPI 4834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.