SCHEMBL17059128

SCHEMBL17059128

C/C=C/CCn1c(=O)n(CC/C=C/C)c(=O)n(CC/C=C/C)c1=O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
CYP3A4 P08684 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19407011 0.91 PDE4A (0.38) CYP3A4
SCHEMBL18598072 0.89 CYP3A4 (0.41) GAACYP3A4NPSR1
SCHEMBL11182708 0.78 GAA (0.44) GAACYP3A4NPSR1APEX1
SCHEMBL11178702 0.75 GAA (0.45) GAACYP3A4NPSR1APEX1
SCHEMBL11174859 0.73 GAA (0.44) GAACYP3A4NPSR1APEX1
SCHEMBL11177882 0.73 GAA (0.44) GAACYP3A4NPSR1APEX1
SCHEMBL4760704 0.70 CYP3A4 (0.38) CYP3A4NPSR1
SCHEMBL11178767 0.70 GAA (0.39) GAACYP3A4NPSR1
SCHEMBL11001667 0.69 CYP3A4 (0.55) GAACYP3A4NPSR1
SCHEMBL7526063 0.69 CYP3A4 (0.36) CYP3A4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005742-B2 Method for producing epoxy compound containing hydrogen peroxide stabilizer NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-26 US disclosed
US-10005742-B2 Method for producing epoxy compound containing hydrogen peroxide stabilizer NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-26 US disclosed
US-20170275258-A1 METHOD FOR PRODUCING EPOXY COMPOUND CONTAINING HYDROGEN PEROXIDE STABILIZER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-09-28 US disclosed
US-20170275258-A1 METHOD FOR PRODUCING EPOXY COMPOUND CONTAINING HYDROGEN PEROXIDE STABILIZER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-09-28 US disclosed
US-9464074-B2 Method for producing epoxy compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-11 US disclosed
US-9464074-B2 Method for producing epoxy compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-11 US disclosed
WO-2016027735-A1 METHOD FOR PRODUCING EPOXY COMPOUND CONTAINING HYDROGEN PEROXIDE STABILIZER 日産化学工業株式会社 2016-02-25 WO disclosed
US-20150284372-A1 METHOD FOR PRODUCING EPOXY COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-10-08 US disclosed
US-20150284372-A1 METHOD FOR PRODUCING EPOXY COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-10-08 US disclosed
EP-2913331-A1 METHOD FOR PRODUCING EPOXY COMPOUND Nissan Chemical Industries, Ltd. (JP) 2015-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275258-A1 METHOD FOR PRODUCING EPOXY COMPOUND CONTAINING HYDROGEN PEROXIDE STABILIZER GPX4, HAO2, HPD GAA 4269/4885CYP3A4 102/4885NPSR1 2946/4885
US-10005742-B2 Method for producing epoxy compound containing hydrogen peroxide stabilizer GPX4, HAO2, HPD GAA 4269/4885CYP3A4 102/4885NPSR1 2946/4885
US-20150284372-A1 METHOD FOR PRODUCING EPOXY COMPOUND NOX5, NOX4, NOXO1 GAA 4540/4885CYP3A4 84/4885NPSR1 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.