Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059420 | 0.87 | HTR7 (0.50) | HTR7HTR1AHTR1DHTR1BHMGB1 | |
| SCHEMBL26418103 | 0.86 | HSD17B1 (0.40) | HTR7HSD17B1MYCKDM4EHTT | |
| SCHEMBL21937531 | 0.84 | HTR7 (0.48) | HTR7HTR1AHTR1DHTR1BHMGB1 | |
| SCHEMBL10936584 | 0.82 | HSD17B1 (0.54) | HSD17B1MYCKDM4EHTTALDH1A1 | |
| SCHEMBL27622429 | 0.80 | HTR7 (0.57) | HTR7HTR1AHTR1DHTR1BHMGB1 | |
| SCHEMBL9838470 | 0.79 | TAAR1 (0.56) | HTR1AHTR1DHTR1BHMGB1HSD17B1 | |
| SCHEMBL28422098 | 0.78 | KDM4E (0.52) | HTR7MYCKDM4EALDH1A1GAA | |
| SCHEMBL11352213 | 0.78 | KDM4E (0.54) | HTR7HMGB1KDM4EALDH1A1RAB9A | |
| SCHEMBL7596912 | 0.76 | NEU3 (0.54) | HTR7HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL3708071 | 0.76 | HTR7 (0.53) | HTR7HTR1AHTR1DHTR1BHMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246958-A1 | BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS | BAIKANG (SUZHOU) CO., LTD (CN) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246958-A1 | BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS | NOS2, EGLN2, HPGD | HTR7 427/4885HTR1A 716/4885HTR1D 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.