SCHEMBL10936584

SCHEMBL10936584

CCc1cc(C(=O)O)ccc1C(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.54
ALDH1A1 P00352 5/20 0.48
RAB9A P51151 3/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
KMT2A Q03164 1/20 0.46
RXRA P19793 4/20 0.45
RXRB P28702 2/20 0.44
RARA P10276 1/20 0.43
RARB P10826 1/20 0.43
RARG P13631 1/20 0.43
RXRG P48443 1/20 0.43
HPGD P15428 2/20 0.42
LMNA P02545 1/20 0.42
MYC P01106 1/20 0.42
KDM4E B2RXH2 4/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277909 0.90 ALDH1A1 (0.54) ALDH1A1RAB9AMEN1NPC1KMT2A
SCHEMBL3230477 0.89 AKR1C3 (0.50) HSD17B1ALDH1A1PKMHTT
SCHEMBL26418103 0.85 HSD17B1 (0.40) HSD17B1ALDH1A1RAB9AHPGDMYC
SCHEMBL7015710 0.85 ALDH1A1 (0.48) HSD17B1ALDH1A1RAB9AMEN1NPC1
SCHEMBL8158109 0.83 ALDH1A1 (0.47) ALDH1A1RAB9AMEN1NPC1KMT2A
SCHEMBL17059409 0.82 HTR7 (0.50) HSD17B1ALDH1A1RAB9AMEN1KMT2A
SCHEMBL717095 0.82 ALDH1A1 (0.54) ALDH1A1RAB9AMEN1NPC1KMT2A
SCHEMBL2000489 0.81 RXRA (0.44) HSD17B1ALDH1A1RAB9AMEN1NPC1
SCHEMBL15568228 0.80 KDM4E (0.51) ALDH1A1RAB9AMEN1NPC1KMT2A
SCHEMBL2755400 0.79 ALDH1A1 (0.56) ALDH1A1RAB9AMEN1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4548811-A COMPRISING A MERCAPTO AND A CYCLODEXTRIN-CARBO KETONE INCLUSION CO SHISEIDO COMPANY LTD. (JP) 1985-10-22 US claimed
US-4547365-A CYCLODEXTRINS AND ALDEHYDE OR KETONE COMPOUNDS; ODORLESS SHISEIDO COMPANY LTD. (JP) 1985-10-15 US claimed
US-4548811-A COMPRISING A MERCAPTO AND A CYCLODEXTRIN-CARBO KETONE INCLUSION CO SHISEIDO COMPANY LTD. (JP) 1985-10-22 US disclosed
US-4547365-A CYCLODEXTRINS AND ALDEHYDE OR KETONE COMPOUNDS; ODORLESS SHISEIDO COMPANY LTD. (JP) 1985-10-15 US disclosed