Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10098778 | 0.76 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL17059930 | 0.75 | CHEK1 (0.60) | SMN1; SMN2PLK4AURKACHEK2CDK1 | |
| SCHEMBL19984763 | 0.75 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL2113682 | 0.75 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL8988 | 0.74 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL10669949 | 0.74 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL11387473 | 0.73 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL17059744 | 0.72 | LMNA (0.46) | L3MBTL1ALDH1A1MAPK1TP53SMN1; SMN2 | |
| SCHEMBL17059747 | 0.72 | MAPT (0.46) | ALDH1A1HPGDTP53POLBMAPT | |
| SCHEMBL10669023 | 0.72 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1ALOX15MAPK10HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| WO-2015129927-A1 | HETEROCYCLIC COMPOUNDS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | BET1, EP300, RBBP5 | L3MBTL1 2394/4885ALDH1A1 3922/4885ALOX15 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.