Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 13/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555698 | 0.87 | LMNA (0.40) | KIF11ALDH1A1LMNAHTT | |
| SCHEMBL13555795 | 0.87 | SIRT2 (0.46) | SIRT2KIF11HPGD | |
| SCHEMBL22470281 | 0.86 | RAB9A (0.49) | KIF11NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17245967 | 0.86 | KIF11 (0.43) | SIRT2KIF11HPGDNPC1RAB9A | |
| SCHEMBL974918 | 0.82 | SIRT2 (0.49) | SIRT2KIF11HPGDNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL7894551 | 0.81 | SIRT2 (0.48) | SIRT2KIF11HPGDNPC1RAB9A | |
| SCHEMBL1906153 | 0.81 | SIRT2 (0.63) | SIRT2KIF11 | |
| SCHEMBL8349509 | 0.81 | KIF11 (0.50) | KIF11 | |
| SCHEMBL11885305 | 0.79 | KIF11 (0.45) | SIRT2KIF11HPGDNPC1RAB9A | |
| SCHEMBL1389497 | 0.79 | KIF11 (0.47) | SIRT2KIF11HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8747810-B2 | Compositions and methods for imaging tissues, organs and tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-10 | — | — | US | disclosed |
| US-8747810-B2 | Compositions and methods for imaging tissues, organs and tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120269724-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120269724-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-10-25 | — | — | US | disclosed |
| EP-2440584-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | President and Fellows of Harvard College (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144891-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010144891-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269724-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | SSTR3, TACR1, SSTR5 | SIRT2 4272/4885KIF11 4726/4885HPGD 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.